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Phleomycin D1 : ウィキペディア英語版
Zeocin

Zeocin is a formulation of phleomycin D1, a glycopeptide antibiotic and one of the phleomycins from ''Streptomyces verticillus'' belonging to the bleomycin family of antibiotics.〔 It is a broad-spectrum antibiotic that is effective against most bacteria, filamentous fungi, yeast, plant, and animal cells. It causes cell death by intercalating into DNA and induces double strand breaks of the DNA.
==Properties==
Zeocin is blue in colour due to the presence of copper ion Cu2+. The copper-chelated form of zeocin is inactive. When zeocin enters a cell, the Cu2+ is reduced to Cu+ and then removed, and zeocin becomes activated and can then bind DNA.〔(【引用サイトリンク】title=Zeocin Selection Reagent - User Guide )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Zeocin」の詳細全文を読む



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